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SMILES: CC(C)c1nc(c([nH]1)-c1ccnc(c1)-c1ccc(cc1)C(=O)NC1CCOCC1)-c1cccc(C)n1

InChI Key: InChIKey=ZNEWDLYYLKDPRH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301169   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
TGF-beta receptor type-1


(Homo sapiens (Human))		BDBM50301169
PNG
(4-(4-(2-isopropyl-4-(6-methylpyridin-2-yl)-1H-imid...)
Show SMILES CC(C)c1nc(c([nH]1)-c1ccnc(c1)-c1ccc(cc1)C(=O)NC1CCOCC1)-c1cccc(C)n1
Show InChI InChI=1S/C29H31N5O2/c1-18(2)28-33-26(27(34-28)24-6-4-5-19(3)31-24)22-11-14-30-25(17-22)20-7-9-21(10-8-20)29(35)32-23-12-15-36-16-13-23/h4-11,14,17-18,23H,12-13,15-16H2,1-3H3,(H,32,35)(H,33,34)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 25n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of TGFR1

Eur J Med Chem 44: 4259-65 (2009)


Article DOI: 10.1016/j.ejmech.2009.07.008
BindingDB Entry DOI: 10.7270/Q2BC3ZM9
More data for this
Ligand-Target Pair