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SMILES: C(NC1CCCOC1)c1ccc(cc1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1

InChI Key: InChIKey=ACIPLQBWITUNBA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301177   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
TGF-beta receptor type-1


(Homo sapiens (Human))		BDBM50301177
PNG
(CHEMBL566234 | N-(4-(4-(3-(pyridin-2-yl)-1H-pyrazo...)
Show SMILES C(NC1CCCOC1)c1ccc(cc1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1
Show InChI InChI=1S/C25H25N5O/c1-2-11-26-23(5-1)25-22(16-29-30-25)20-10-12-27-24(14-20)19-8-6-18(7-9-19)15-28-21-4-3-13-31-17-21/h1-2,5-12,14,16,21,28H,3-4,13,15,17H2,(H,29,30)
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UniChem

Similars
Article
PubMed
n/an/a 47n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of TGFR1

Eur J Med Chem 44: 4259-65 (2009)


Article DOI: 10.1016/j.ejmech.2009.07.008
BindingDB Entry DOI: 10.7270/Q2BC3ZM9
More data for this
Ligand-Target Pair