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SMILES: Cc1cccc(n1)-c1nc(CNc2ccc(cc2)C(N)=O)[nH]c1C1=CC2N=CCNC2C=C1

InChI Key: InChIKey=WTBLUKVFCSUYHD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301182   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
TGF-beta receptor type-1


(Homo sapiens (Human))		BDBM50301182
PNG
(4-((5-(6-methylpyridin-2-yl)-4-(1,4,4a,8a-tetrahyd...)
Show SMILES Cc1cccc(n1)-c1nc(CNc2ccc(cc2)C(N)=O)[nH]c1C1=CC2N=CCNC2C=C1 |c:29,35,t:26|
Show InChI InChI=1S/C25H25N7O/c1-15-3-2-4-20(30-15)24-23(17-7-10-19-21(13-17)28-12-11-27-19)31-22(32-24)14-29-18-8-5-16(6-9-18)25(26)33/h2-10,12-13,19,21,27,29H,11,14H2,1H3,(H2,26,33)(H,31,32)
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PC cid
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UniChem

Similars
Article
PubMed
n/an/a 75n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of TGFR1

Eur J Med Chem 44: 4259-65 (2009)


Article DOI: 10.1016/j.ejmech.2009.07.008
BindingDB Entry DOI: 10.7270/Q2BC3ZM9
More data for this
Ligand-Target Pair