BindingDB logo
myBDB logout

BDBM50301331 5-chloro-6-(1'-(4-chlorobenzyl)-4,4'-bipiperidin-1-yl)-N-(3,4-dichlorobenzyl)nicotinamide::CHEMBL570958

SMILES: Clc1ccc(CN2CCC(CC2)C2CCN(CC2)c2ncc(cc2Cl)C(=O)NCc2ccc(Cl)c(Cl)c2)cc1

InChI Key: InChIKey=NIBPZSMLIVDUPL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301331   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
chemokine (C-X-C motif) receptor 3


(Homo sapiens (Human))		BDBM50301331
PNG
(5-chloro-6-(1'-(4-chlorobenzyl)-4,4'-bipiperidin-1...)
Show SMILES Clc1ccc(CN2CCC(CC2)C2CCN(CC2)c2ncc(cc2Cl)C(=O)NCc2ccc(Cl)c(Cl)c2)cc1
Show InChI InChI=1S/C30H32Cl4N4O/c31-25-4-1-20(2-5-25)19-37-11-7-22(8-12-37)23-9-13-38(14-10-23)29-28(34)16-24(18-35-29)30(39)36-17-21-3-6-26(32)27(33)15-21/h1-6,15-16,18,22-23H,7-14,17,19H2,(H,36,39)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 2.70E+3n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of 125I-IP10 from recombinant human CXCR3 receptor expressed in Ba/F3 cell membrane after 1 to 4 hrs by scintillation counting

Bioorg Med Chem Lett 19: 5205-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.020
BindingDB Entry DOI: 10.7270/Q21V5F18
More data for this
Ligand-Target Pair