BDBM50301563 CHEMBL568099::N-(4-carbamimidoylbenzyl)-2-(1-(2-methoxy-4-methylphenylsulfonamido)-4-methyl-2-oxo-1,2,5,6-tetrahydropyridin-3-yl)acetamide

SMILES: COc1cc(C)ccc1S(=O)(=O)NN1CCC(C)=C(CC(=O)NCc2ccc(cc2)C(N)=N)C1=O

InChI Key: InChIKey=PFZUZXQKZIJFGZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301563   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50301563 (CHEMBL568099 | N-(4-carbamimidoylbenzyl)-2-(1-(2-m...) Show SMILES COc1cc(C)ccc1S(=O)(=O)NN1CCC(C)=C(CC(=O)NCc2ccc(cc2)C(N)=N)C1=O |t:18| Show InChI InChI=1S/C24H29N5O5S/c1-15-4-9-21(20(12-15)34-3)35(32,33)28-29-11-10-16(2)19(24(29)31)13-22(30)27-14-17-5-7-18(8-6-17)23(25)26/h4-9,12,28H,10-11,13-14H2,1-3H3,(H3,25,26)(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Inhibition of human thrombin				Bioorg Med Chem Lett 19: 5429-32 (2009) Article DOI: 10.1016/j.bmcl.2009.07.107 BindingDB Entry DOI: 10.7270/Q2MP53BQ
					More data for this Ligand-Target Pair