BDBM50301660 CHEMBL565826::trans-N-(5-(2-(fluoromethoxy)phenyl)pyrimidin-2-yl)-1'-oxo-1'H-spiro[cyclohexane-1,3'-furo[3,4-c]pyridine]-4-carboxamide

SMILES: FCOc1ccccc1-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ccncc32)nc1

InChI Key: InChIKey=FWLHMGTVSANAAF-AOVWKMQPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301660   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50301660 (CHEMBL565826 | trans-N-(5-(2-(fluoromethoxy)phenyl...) Show SMILES FCOc1ccccc1-c1cnc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ccncc32)nc1 |r,wU:19.23,wD:16.16,(4.65,-20.86,;3.32,-20.09,;1.99,-20.87,;1.99,-22.41,;3.33,-23.17,;3.33,-24.72,;2,-25.49,;.67,-24.72,;.67,-23.18,;-.67,-22.41,;-2,-23.18,;-3.33,-22.41,;-3.33,-20.87,;-4.66,-20.1,;-5.99,-20.87,;-7.33,-20.1,;-5.99,-22.41,;-7.32,-23.19,;-7.32,-24.73,;-5.99,-25.49,;-4.66,-24.73,;-4.66,-23.19,;-5.07,-26.74,;-5.98,-28,;-5.49,-29.46,;-7.46,-27.53,;-8.8,-28.3,;-10.13,-27.53,;-10.13,-25.99,;-8.8,-25.21,;-7.47,-25.98,;-2,-20.1,;-.67,-20.86,)| Show InChI InChI=1S/C24H21FN4O4/c25-14-32-20-4-2-1-3-17(20)16-11-27-23(28-12-16)29-21(30)15-5-8-24(9-6-15)19-13-26-10-7-18(19)22(31)33-24/h1-4,7,10-13,15H,5-6,8-9,14H2,(H,27,28,29,30)/t15-,24-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cells				Bioorg Med Chem Lett 19: 5436-9 (2009) Article DOI: 10.1016/j.bmcl.2009.07.103 BindingDB Entry DOI: 10.7270/Q27D2V6Q
					More data for this Ligand-Target Pair