null

SMILES: Fc1cc2COC3(CCN(Cc4ccc(Oc5ccc(F)c(F)c5)cc4)CC3)c2cn1

InChI Key: InChIKey=JFJGUHDHENWREH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301696   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50301696 (1'-(4-(3,4-difluorophenoxy)benzyl)-6-fluoro-1H-spi...) Show SMILES Fc1cc2COC3(CCN(Cc4ccc(Oc5ccc(F)c(F)c5)cc4)CC3)c2cn1 Show InChI InChI=1S/C24H21F3N2O2/c25-21-6-5-19(12-22(21)26)31-18-3-1-16(2-4-18)14-29-9-7-24(8-10-29)20-13-28-23(27)11-17(20)15-30-24/h1-6,11-13H,7-10,14-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [35S]MK-499 from human ERG expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5339-45 (2009) Article DOI: 10.1016/j.bmcl.2009.07.132 BindingDB Entry DOI: 10.7270/Q27P90BK
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50301696 (1'-(4-(3,4-difluorophenoxy)benzyl)-6-fluoro-1H-spi...) Show SMILES Fc1cc2COC3(CCN(Cc4ccc(Oc5ccc(F)c(F)c5)cc4)CC3)c2cn1 Show InChI InChI=1S/C24H21F3N2O2/c25-21-6-5-19(12-22(21)26)31-18-3-1-16(2-4-18)14-29-9-7-24(8-10-29)20-13-28-23(27)11-17(20)15-30-24/h1-6,11-13H,7-10,14-15H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1R expressed in CHO cells				Bioorg Med Chem Lett 19: 5339-45 (2009) Article DOI: 10.1016/j.bmcl.2009.07.132 BindingDB Entry DOI: 10.7270/Q27P90BK
					More data for this Ligand-Target Pair