BDBM50301706 (Z)-(3,4-difluorophenyl)(5-((6-fluoro-1H-spiro[furo[3,4-c]pyridine-3,4'-piperidine]-1'-yl)methyl)pyridin-2-yl)methanone O-ethyl oxime::CHEMBL582792
SMILES: CCO\N=C(\c1ccc(F)c(F)c1)c1ccc(CN2CCC3(CC2)OCc2cc(F)ncc32)cn1
InChI Key: InChIKey=RAVKUBUGSJSXIV-MKCFTUBBSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50301706 ((Z)-(3,4-difluorophenyl)(5-((6-fluoro-1H-spiro[fur...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute Curated by ChEMBL | Assay Description Displacement of [35S]MK-499 from human ERG expressed in HEK293 cells | Bioorg Med Chem Lett 19: 5339-45 (2009) Article DOI: 10.1016/j.bmcl.2009.07.132 BindingDB Entry DOI: 10.7270/Q27P90BK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50301706 ((Z)-(3,4-difluorophenyl)(5-((6-fluoro-1H-spiro[fur...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.350 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute Curated by ChEMBL | Assay Description Displacement of [125I]MCH from human MCH1R expressed in CHO cells | Bioorg Med Chem Lett 19: 5339-45 (2009) Article DOI: 10.1016/j.bmcl.2009.07.132 BindingDB Entry DOI: 10.7270/Q27P90BK | |||||||||||
More data for this Ligand-Target Pair |