BDBM50301711 (1R,2R)-2-(5-(3-methoxyphenyl)isoxazol-3-yl)-N-(1-phenylcyclobutyl)cyclopentanecarboxamide::CHEMBL585204

SMILES: COc1cccc(c1)-c1cc(no1)[C@@H]1CCC[C@H]1C(=O)NC1(CCC1)c1ccccc1

InChI Key: InChIKey=GDJDQBQHVCUXKE-FGZHOGPDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301711   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50301711 ((1R,2R)-2-(5-(3-methoxyphenyl)isoxazol-3-yl)-N-(1-...) Show SMILES COc1cccc(c1)-c1cc(no1)[C@@H]1CCC[C@H]1C(=O)NC1(CCC1)c1ccccc1 |r| Show InChI InChI=1S/C26H28N2O3/c1-30-20-11-5-8-18(16-20)24-17-23(28-31-24)21-12-6-13-22(21)25(29)27-26(14-7-15-26)19-9-3-2-4-10-19/h2-5,8-11,16-17,21-22H,6-7,12-15H2,1H3,(H,27,29)/t21-,22-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 channel expressed in HEK293 cells by FRET assay				Bioorg Med Chem Lett 19: 5334-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.135 BindingDB Entry DOI: 10.7270/Q2QF8SZQ
					More data for this Ligand-Target Pair