BDBM50301719 (1R,2R)-N-(1-phenylcyclobutyl)-2-(5-(6-(trifluoromethyl)pyridin-2-yl)isoxazol-3-yl)cyclopentanecarboxamide::CHEMBL579061

SMILES: FC(F)(F)c1cccc(n1)-c1cc(no1)[C@@H]1CCC[C@H]1C(=O)NC1(CCC1)c1ccccc1

InChI Key: InChIKey=COGOKAALKMEACZ-QZTJIDSGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301719   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50301719 ((1R,2R)-N-(1-phenylcyclobutyl)-2-(5-(6-(trifluorom...) Show SMILES FC(F)(F)c1cccc(n1)-c1cc(no1)[C@@H]1CCC[C@H]1C(=O)NC1(CCC1)c1ccccc1 |r| Show InChI InChI=1S/C25H24F3N3O2/c26-25(27,28)22-12-5-11-19(29-22)21-15-20(31-33-21)17-9-4-10-18(17)23(32)30-24(13-6-14-24)16-7-2-1-3-8-16/h1-3,5,7-8,11-12,15,17-18H,4,6,9-10,13-14H2,(H,30,32)/t17-,18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 channel expressed in HEK293 cells by FRET assay				Bioorg Med Chem Lett 19: 5334-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.135 BindingDB Entry DOI: 10.7270/Q2QF8SZQ
					More data for this Ligand-Target Pair