BDBM50301746 5-(4-chlorophenyl)-3-(1-cyclohexyl-1H-imidazol-4-yl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole::CHEMBL585095

SMILES: Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1cn(cn1)C1CCCCC1

InChI Key: InChIKey=DTBAXFXZDCEJJK-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301746   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50301746 (5-(4-chlorophenyl)-3-(1-cyclohexyl-1H-imidazol-4-y...) Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1cn(cn1)C1CCCCC1 Show InChI InChI=1S/C25H23Cl3N4/c1-16-24(22-14-31(15-29-22)20-5-3-2-4-6-20)30-32(23-12-11-19(27)13-21(23)28)25(16)17-7-9-18(26)10-8-17/h7-15,20H,2-6H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor transfected in CHO-K1cells by GTPgamma[35S] binding assay				Bioorg Med Chem Lett 19: 5351-4 (2009) Article DOI: 10.1016/j.bmcl.2009.07.130 BindingDB Entry DOI: 10.7270/Q2KP827S
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50301746 (5-(4-chlorophenyl)-3-(1-cyclohexyl-1H-imidazol-4-y...) Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)-c1cn(cn1)C1CCCCC1 Show InChI InChI=1S/C25H23Cl3N4/c1-16-24(22-14-31(15-29-22)20-5-3-2-4-6-20)30-32(23-12-11-19(27)13-21(23)28)25(16)17-7-9-18(26)10-8-17/h7-15,20H,2-6H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from rat brain CB1 receptor				Bioorg Med Chem Lett 19: 5351-4 (2009) Article DOI: 10.1016/j.bmcl.2009.07.130 BindingDB Entry DOI: 10.7270/Q2KP827S
					More data for this Ligand-Target Pair