BDBM50302203 3-amino-4-(2-methoxyethoxy)thieno[2,3-b]pyridine-2-carboxamide::CHEMBL570264

SMILES: COCCOc1ccnc2sc(C(N)=O)c(N)c12

InChI Key: InChIKey=XXAOTMJPHSPQJX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50302203   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM50302203 (3-amino-4-(2-methoxyethoxy)thieno[2,3-b]pyridine-2...) Show SMILES COCCOc1ccnc2sc(C(N)=O)c(N)c12 Show InChI InChI=1S/C11H13N3O3S/c1-16-4-5-17-6-2-3-14-11-7(6)8(12)9(18-11)10(13)15/h2-3H,4-5,12H2,1H3,(H2,13,15)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Flag epitope-tagged IKK-beta preincubated for 5 mins by scintillation proximity assay				Bioorg Med Chem Lett 19: 5547-51 (2009) Article DOI: 10.1016/j.bmcl.2009.08.054 BindingDB Entry DOI: 10.7270/Q22Z16G1
					More data for this Ligand-Target Pair