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SMILES: CCc1n[nH]c(CC)c1Oc1cc(cc(c1)C#N)C#N

InChI Key: InChIKey=LTSBRJXQVVZDJZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50302396   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))		BDBM50302396
PNG
(5-(3,5-diethyl-1H-pyrazol-4-yloxy)isophthalonitril...)
Show SMILES CCc1n[nH]c(CC)c1Oc1cc(cc(c1)C#N)C#N
Show InChI InChI=1S/C15H14N4O/c1-3-13-15(14(4-2)19-18-13)20-12-6-10(8-16)5-11(7-12)9-17/h5-7H,3-4H2,1-2H3,(H,18,19)
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Article
PubMed
n/an/a 9.80E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells

Bioorg Med Chem Lett 19: 5857-60 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.080
BindingDB Entry DOI: 10.7270/Q2R78F8V
More data for this
Ligand-Target Pair