BDBM50302402 7-bromo-2-(2-chloro-6-fluorophenyl)-1H-phenanthro[9,10-d]imidazole::CHEMBL566261

SMILES: Fc1cccc(Cl)c1-c1nc2c([nH]1)c1cccc(Br)c1c1ccccc21

InChI Key: InChIKey=KLDPORRVVYLMRJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302402   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase (Homo sapiens (Human))	BDBM50302402 (7-bromo-2-(2-chloro-6-fluorophenyl)-1H-phenanthro[...) Show SMILES Fc1cccc(Cl)c1-c1nc2c([nH]1)c1cccc(Br)c1c1ccccc21 Show InChI InChI=1S/C21H11BrClFN2/c22-14-8-3-7-13-17(14)11-5-1-2-6-12(11)19-20(13)26-21(25-19)18-15(23)9-4-10-16(18)24/h1-10H,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cells				Bioorg Med Chem Lett 19: 5837-41 (2009) Article DOI: 10.1016/j.bmcl.2009.08.085 BindingDB Entry DOI: 10.7270/Q2MG7PKK
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM50302402 (7-bromo-2-(2-chloro-6-fluorophenyl)-1H-phenanthro[...) Show SMILES Fc1cccc(Cl)c1-c1nc2c([nH]1)c1cccc(Br)c1c1ccccc21 Show InChI InChI=1S/C21H11BrClFN2/c22-14-8-3-7-13-17(14)11-5-1-2-6-12(11)19-20(13)26-21(25-19)18-15(23)9-4-10-16(18)24/h1-10H,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of mPGES1 in IL-1beta-stimulated human A549 cells assessed as blockade of PGH2 to PGE2 conversion in presence of 50% fetal bovine serum				Bioorg Med Chem Lett 19: 5837-41 (2009) Article DOI: 10.1016/j.bmcl.2009.08.085 BindingDB Entry DOI: 10.7270/Q2MG7PKK
					More data for this Ligand-Target Pair