BDBM50302518 4-(6-chloro-1H-indol-5-ylamino)-5-styrylnicotinonitrile::CHEMBL578169

SMILES: Clc1cc2[nH]ccc2cc1Nc1c(\C=C\c2ccccc2)cncc1C#N

InChI Key: InChIKey=KAWMNMBJDDWUNT-VOTSOKGWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302518   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50302518 (4-(6-chloro-1H-indol-5-ylamino)-5-styrylnicotinoni...) Show SMILES Clc1cc2[nH]ccc2cc1Nc1c(\C=C\c2ccccc2)cncc1C#N Show InChI InChI=1S/C22H15ClN4/c23-19-11-20-16(8-9-26-20)10-21(19)27-22-17(13-25-14-18(22)12-24)7-6-15-4-2-1-3-5-15/h1-11,13-14,26H,(H,25,27)/b7-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta by IMAP kinase assay				Bioorg Med Chem Lett 19: 5829-32 (2009) Article DOI: 10.1016/j.bmcl.2009.08.086 BindingDB Entry DOI: 10.7270/Q2ZS2WKC
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50302518 (4-(6-chloro-1H-indol-5-ylamino)-5-styrylnicotinoni...) Show SMILES Clc1cc2[nH]ccc2cc1Nc1c(\C=C\c2ccccc2)cncc1C#N Show InChI InChI=1S/C22H15ClN4/c23-19-11-20-16(8-9-26-20)10-21(19)27-22-17(13-25-14-18(22)12-24)7-6-15-4-2-1-3-5-15/h1-11,13-14,26H,(H,25,27)/b7-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP kinase assay				Bioorg Med Chem Lett 19: 5829-32 (2009) Article DOI: 10.1016/j.bmcl.2009.08.086 BindingDB Entry DOI: 10.7270/Q2ZS2WKC
					More data for this Ligand-Target Pair