BDBM50302519 4-(7-chloro-4-methyl-1H-indol-5-ylamino)-5-styrylnicotinonitrile::CHEMBL568687

SMILES: Cc1c(Nc2c(\C=C\c3ccccc3)cncc2C#N)cc(Cl)c2[nH]ccc12

InChI Key: InChIKey=QEQRMPXQCBZMSU-BQYQJAHWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302519   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50302519 (4-(7-chloro-4-methyl-1H-indol-5-ylamino)-5-styryln...) Show SMILES Cc1c(Nc2c(\C=C\c3ccccc3)cncc2C#N)cc(Cl)c2[nH]ccc12 Show InChI InChI=1S/C23H17ClN4/c1-15-19-9-10-27-23(19)20(24)11-21(15)28-22-17(13-26-14-18(22)12-25)8-7-16-5-3-2-4-6-16/h2-11,13-14,27H,1H3,(H,26,28)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta by IMAP kinase assay				Bioorg Med Chem Lett 19: 5829-32 (2009) Article DOI: 10.1016/j.bmcl.2009.08.086 BindingDB Entry DOI: 10.7270/Q2ZS2WKC
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50302519 (4-(7-chloro-4-methyl-1H-indol-5-ylamino)-5-styryln...) Show SMILES Cc1c(Nc2c(\C=C\c3ccccc3)cncc2C#N)cc(Cl)c2[nH]ccc12 Show InChI InChI=1S/C23H17ClN4/c1-15-19-9-10-27-23(19)20(24)11-21(15)28-22-17(13-26-14-18(22)12-25)8-7-16-5-3-2-4-6-16/h2-11,13-14,27H,1H3,(H,26,28)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP kinase assay				Bioorg Med Chem Lett 19: 5829-32 (2009) Article DOI: 10.1016/j.bmcl.2009.08.086 BindingDB Entry DOI: 10.7270/Q2ZS2WKC
					More data for this Ligand-Target Pair