BDBM50302523 4-(4-methyl-1H-indol-5-ylamino)-5-phenethylnicotinonitrile::CHEMBL578783

SMILES: Cc1c(Nc2c(CCc3ccccc3)cncc2C#N)ccc2[nH]ccc12

InChI Key: InChIKey=SBTUVVZTMJEJMZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302523   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50302523 (4-(4-methyl-1H-indol-5-ylamino)-5-phenethylnicotin...) Show SMILES Cc1c(Nc2c(CCc3ccccc3)cncc2C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C23H20N4/c1-16-20-11-12-26-22(20)10-9-21(16)27-23-18(14-25-15-19(23)13-24)8-7-17-5-3-2-4-6-17/h2-6,9-12,14-15,26H,7-8H2,1H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta by IMAP kinase assay				Bioorg Med Chem Lett 19: 5829-32 (2009) Article DOI: 10.1016/j.bmcl.2009.08.086 BindingDB Entry DOI: 10.7270/Q2ZS2WKC
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50302523 (4-(4-methyl-1H-indol-5-ylamino)-5-phenethylnicotin...) Show SMILES Cc1c(Nc2c(CCc3ccccc3)cncc2C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C23H20N4/c1-16-20-11-12-26-22(20)10-9-21(16)27-23-18(14-25-15-19(23)13-24)8-7-17-5-3-2-4-6-17/h2-6,9-12,14-15,26H,7-8H2,1H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP kinase assay				Bioorg Med Chem Lett 19: 5829-32 (2009) Article DOI: 10.1016/j.bmcl.2009.08.086 BindingDB Entry DOI: 10.7270/Q2ZS2WKC
					More data for this Ligand-Target Pair