BDBM50302581 1-(4-methoxy-2-methylphenyl)-3,6-dimethyl-N-(pentan-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL565442

SMILES: CCC(CC)Nc1nc(C)nc2n(nc(C)c12)-c1ccc(OC)cc1C

InChI Key: InChIKey=BLAJJXCTANZRDH-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50302581   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50302581 (1-(4-methoxy-2-methylphenyl)-3,6-dimethyl-N-(penta...) Show SMILES CCC(CC)Nc1nc(C)nc2n(nc(C)c12)-c1ccc(OC)cc1C Show InChI InChI=1S/C20H27N5O/c1-7-15(8-2)23-19-18-13(4)24-25(20(18)22-14(5)21-19)17-10-9-16(26-6)11-12(17)3/h9-11,15H,7-8H2,1-6H3,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP production				Bioorg Med Chem Lett 19: 6144-7 (2009) Article DOI: 10.1016/j.bmcl.2009.09.016 BindingDB Entry DOI: 10.7270/Q2FT8M46
					More data for this Ligand-Target Pair