BDBM50302824 2-(4-(2-(2,4-dichlorophenylsulfonamido)-4-(ethylcarbamoyl)phenoxy)-3,5-dimethoxyphenyl)acetic acid::CHEMBL570653

SMILES: CCNC(=O)c1ccc(Oc2c(OC)cc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1

InChI Key: InChIKey=JHMCYEDYNPVSNL-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50302824   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50302824 (2-(4-(2-(2,4-dichlorophenylsulfonamido)-4-(ethylca...) Show SMILES CCNC(=O)c1ccc(Oc2c(OC)cc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C25H24Cl2N2O8S/c1-4-28-25(32)15-5-7-19(18(12-15)29-38(33,34)22-8-6-16(26)13-17(22)27)37-24-20(35-2)9-14(11-23(30)31)10-21(24)36-3/h5-10,12-13,29H,4,11H2,1-3H3,(H,28,32)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by scintillation counting in presence of 50 % human plasma				Bioorg Med Chem Lett 22: 367-70 (2011) Article DOI: 10.1016/j.bmcl.2011.10.123 BindingDB Entry DOI: 10.7270/Q2057GB8
					More data for this Ligand-Target Pair
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50302824 (2-(4-(2-(2,4-dichlorophenylsulfonamido)-4-(ethylca...) Show SMILES CCNC(=O)c1ccc(Oc2c(OC)cc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C25H24Cl2N2O8S/c1-4-28-25(32)15-5-7-19(18(12-15)29-38(33,34)22-8-6-16(26)13-17(22)27)37-24-20(35-2)9-14(11-23(30)31)10-21(24)36-3/h5-10,12-13,29H,4,11H2,1-3H3,(H,28,32)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA				Bioorg Med Chem Lett 22: 367-70 (2011) Article DOI: 10.1016/j.bmcl.2011.10.123 BindingDB Entry DOI: 10.7270/Q2057GB8
					More data for this Ligand-Target Pair
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50302824 (2-(4-(2-(2,4-dichlorophenylsulfonamido)-4-(ethylca...) Show SMILES CCNC(=O)c1ccc(Oc2c(OC)cc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C25H24Cl2N2O8S/c1-4-28-25(32)15-5-7-19(18(12-15)29-38(33,34)22-8-6-16(26)13-17(22)27)37-24-20(35-2)9-14(11-23(30)31)10-21(24)36-3/h5-10,12-13,29H,4,11H2,1-3H3,(H,28,32)(H,30,31)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGD2 from human DP receptor expressed in HEK 293 cells in presence of 0.5% BSA by scintillation counting				Bioorg Med Chem Lett 19: 6419-23 (2009) Article DOI: 10.1016/j.bmcl.2009.09.052 BindingDB Entry DOI: 10.7270/Q25Q4X20
					More data for this Ligand-Target Pair
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50302824 (2-(4-(2-(2,4-dichlorophenylsulfonamido)-4-(ethylca...) Show SMILES CCNC(=O)c1ccc(Oc2c(OC)cc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C25H24Cl2N2O8S/c1-4-28-25(32)15-5-7-19(18(12-15)29-38(33,34)22-8-6-16(26)13-17(22)27)37-24-20(35-2)9-14(11-23(30)31)10-21(24)36-3/h5-10,12-13,29H,4,11H2,1-3H3,(H,28,32)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-PGD2 from human CRTH2 expressed in HEK 293 cells in presence of 0.5% BSA by scintillation counting				Bioorg Med Chem Lett 19: 6419-23 (2009) Article DOI: 10.1016/j.bmcl.2009.09.052 BindingDB Entry DOI: 10.7270/Q25Q4X20
					More data for this Ligand-Target Pair
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50302824 (2-(4-(2-(2,4-dichlorophenylsulfonamido)-4-(ethylca...) Show SMILES CCNC(=O)c1ccc(Oc2c(OC)cc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C25H24Cl2N2O8S/c1-4-28-25(32)15-5-7-19(18(12-15)29-38(33,34)22-8-6-16(26)13-17(22)27)37-24-20(35-2)9-14(11-23(30)31)10-21(24)36-3/h5-10,12-13,29H,4,11H2,1-3H3,(H,28,32)(H,30,31)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA				Bioorg Med Chem Lett 22: 367-70 (2011) Article DOI: 10.1016/j.bmcl.2011.10.123 BindingDB Entry DOI: 10.7270/Q2057GB8
					More data for this Ligand-Target Pair