BDBM50302970 (R)-3-amino-1-((S)-2-(5-(1-fluorocyclopropyl)-1,2,4-oxadiazol-3-yl)pyrrolidin-1-yl)-4-(2,4,5-trifluorophenyl)butan-1-one::CHEMBL585290

SMILES: N[C@@H](CC(=O)N1CCC[C@H]1c1noc(n1)C1(F)CC1)Cc1cc(F)c(F)cc1F

InChI Key: InChIKey=IBCCTHCYTJUQQX-ABAIWWIYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50302970   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50302970 ((R)-3-amino-1-((S)-2-(5-(1-fluorocyclopropyl)-1,2,...) Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1c1noc(n1)C1(F)CC1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C19H20F4N4O2/c20-12-9-14(22)13(21)7-10(12)6-11(24)8-16(28)27-5-1-2-15(27)17-25-18(29-26-17)19(23)3-4-19/h7,9,11,15H,1-6,8,24H2/t11-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Santhera Pharmaceuticals (Switzerland) Ltd Curated by ChEMBL					Assay Description Inhibition of DPP7				Bioorg Med Chem Lett 19: 6340-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50302970 ((R)-3-amino-1-((S)-2-(5-(1-fluorocyclopropyl)-1,2,...) Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1c1noc(n1)C1(F)CC1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C19H20F4N4O2/c20-12-9-14(22)13(21)7-10(12)6-11(24)8-16(28)27-5-1-2-15(27)17-25-18(29-26-17)19(23)3-4-19/h7,9,11,15H,1-6,8,24H2/t11-,15+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Santhera Pharmaceuticals (Switzerland) Ltd Curated by ChEMBL					Assay Description Inhibition of human DPP9 expressed in baculovirus system after 30 mins by continuous fluorescent assay				Bioorg Med Chem Lett 19: 6340-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50302970 ((R)-3-amino-1-((S)-2-(5-(1-fluorocyclopropyl)-1,2,...) Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1c1noc(n1)C1(F)CC1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C19H20F4N4O2/c20-12-9-14(22)13(21)7-10(12)6-11(24)8-16(28)27-5-1-2-15(27)17-25-18(29-26-17)19(23)3-4-19/h7,9,11,15H,1-6,8,24H2/t11-,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Santhera Pharmaceuticals (Switzerland) Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP4 transfected in Pichia methanolica expression system after 10 mins by continuous fluorimetric assay				Bioorg Med Chem Lett 19: 6340-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50302970 ((R)-3-amino-1-((S)-2-(5-(1-fluorocyclopropyl)-1,2,...) Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1c1noc(n1)C1(F)CC1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C19H20F4N4O2/c20-12-9-14(22)13(21)7-10(12)6-11(24)8-16(28)27-5-1-2-15(27)17-25-18(29-26-17)19(23)3-4-19/h7,9,11,15H,1-6,8,24H2/t11-,15+/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Santhera Pharmaceuticals (Switzerland) Ltd Curated by ChEMBL					Assay Description Inhibition of human DPP8 expressed in baculovirus system after 15 mins by continuous fluorescent assay				Bioorg Med Chem Lett 19: 6340-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50302970 ((R)-3-amino-1-((S)-2-(5-(1-fluorocyclopropyl)-1,2,...) Show SMILES N[C@@H](CC(=O)N1CCC[C@H]1c1noc(n1)C1(F)CC1)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C19H20F4N4O2/c20-12-9-14(22)13(21)7-10(12)6-11(24)8-16(28)27-5-1-2-15(27)17-25-18(29-26-17)19(23)3-4-19/h7,9,11,15H,1-6,8,24H2/t11-,15+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Santhera Pharmaceuticals (Switzerland) Ltd Curated by ChEMBL					Assay Description Inhibition of human POP expressed in Escherichia coli after 30 mins by continuous fluorescent assay				Bioorg Med Chem Lett 19: 6340-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.078 BindingDB Entry DOI: 10.7270/Q2WS8TB2
					More data for this Ligand-Target Pair