BDBM50303147 (-)-licarin B::CHEMBL578403
SMILES: COc1cc(\C=C\C)cc2[C@H](C)[C@H](Oc12)c1ccc2OCOc2c1
InChI Key: InChIKey=DMMQXURQRMNSBM-NSWCWGQASA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sialidase A (Streptococcus pneumoniae) | BDBM50303147 ((-)-licarin B | CHEMBL578403) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Bioscience and Biotechnology Curated by ChEMBL | Assay Description Noncompetitive inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60... | Bioorg Med Chem Lett 27: 3060-3064 (2017) Article DOI: 10.1016/j.bmcl.2017.05.055 BindingDB Entry DOI: 10.7270/Q2G73H5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase A (NanA) (Streptococcus pneumoniae) | BDBM50303147 ((-)-licarin B | CHEMBL578403) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Bioscience and Biotechnology Curated by ChEMBL | Assay Description Inhibition of Streptococcus pneumoniae sialidase NanA using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid as substrate after 60 mins by FRET a... | Bioorg Med Chem Lett 27: 3060-3064 (2017) Article DOI: 10.1016/j.bmcl.2017.05.055 BindingDB Entry DOI: 10.7270/Q2G73H5Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase (cyclooxygenase) (Ovis aries (Sheep)) | BDBM50303147 ((-)-licarin B | CHEMBL578403) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.66E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Nacional de Colombia Curated by ChEMBL | Assay Description Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA | Bioorg Med Chem Lett 19: 6922-5 (2009) Article DOI: 10.1016/j.bmcl.2009.10.069 BindingDB Entry DOI: 10.7270/Q2J1043X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase (Cyclooxygenase-2) (Ovis aries (Sheep)) | BDBM50303147 ((-)-licarin B | CHEMBL578403) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.56E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Nacional de Colombia Curated by ChEMBL | Assay Description Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA | Bioorg Med Chem Lett 19: 6922-5 (2009) Article DOI: 10.1016/j.bmcl.2009.10.069 BindingDB Entry DOI: 10.7270/Q2J1043X | |||||||||||
More data for this Ligand-Target Pair |