BDBM50303152 CHEMBL571616::Ocophyllals A
SMILES: COc1cc(C=O)cc2c(C)c(oc12)-c1ccc2OCOc2c1
InChI Key: InChIKey=HCCYBFOBGKSPJH-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 2 (Ovis aries (Sheep)) | BDBM50303152 (CHEMBL571616 | Ocophyllals A) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.68E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Nacional de Colombia Curated by ChEMBL | Assay Description Inhibition of ovine COX-2 assessed as inhibition of transformation of AA to PGH2 by EIA | Bioorg Med Chem Lett 19: 6922-5 (2009) Article DOI: 10.1016/j.bmcl.2009.10.069 BindingDB Entry DOI: 10.7270/Q2J1043X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50303152 (CHEMBL571616 | Ocophyllals A) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.23E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Nacional de Colombia Curated by ChEMBL | Assay Description Inhibition of ovine COX-1 assessed as inhibition of transformation of AA to PGH2 by EIA | Bioorg Med Chem Lett 19: 6922-5 (2009) Article DOI: 10.1016/j.bmcl.2009.10.069 BindingDB Entry DOI: 10.7270/Q2J1043X | |||||||||||
More data for this Ligand-Target Pair |