BindingDB PrimarySearch

null

SMILES: OS(=O)(=O)CCN1C(=S)S\C(=C/c2cn(nc2-c2ccc(OCc3ccccc3F)cc2)-c2ccccc2)C1=O

InChI Key: InChIKey=YSZRDGCESQUOBE-XYGWBWBKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50303174
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50303174 (2-(5-((3-(4-(2-fluorobenzyloxy)phenyl)-1-phenyl-1H...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	4.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2GM85XC
					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50303174 (2-(5-((3-(4-(2-fluorobenzyloxy)phenyl)-1-phenyl-1H...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay									PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2JD4VDZ
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50303174 (2-(5-((3-(4-(2-fluorobenzyloxy)phenyl)-1-phenyl-1H...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of recombinant PTP1B				J Med Chem 52: 6716-23 (2009) Article DOI: 10.1021/jm901016k BindingDB Entry DOI: 10.7270/Q2VX0GK3
Institute for Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase C (Homo sapiens (Human))	BDBM50303174 (2-(5-((3-(4-(2-fluorobenzyloxy)phenyl)-1-phenyl-1H...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of recombinant CD45				J Med Chem 52: 6716-23 (2009) Article DOI: 10.1021/jm901016k BindingDB Entry DOI: 10.7270/Q2VX0GK3
Institute for Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 3 (Homo sapiens (Human))	BDBM50303174 (2-(5-((3-(4-(2-fluorobenzyloxy)phenyl)-1-phenyl-1H...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Max-Planck-Institute of Molecular Physiology Curated by ChEMBL					Assay Description Inhibition of VHR				Bioorg Med Chem 19: 2145-55 (2011) Article DOI: 10.1016/j.bmc.2011.02.047 BindingDB Entry DOI: 10.7270/Q2BR8SHK
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 7 (Homo sapiens (Human))	BDBM50303174 (2-(5-((3-(4-(2-fluorobenzyloxy)phenyl)-1-phenyl-1H...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of recombinant HePTP				J Med Chem 52: 6716-23 (2009) Article DOI: 10.1021/jm901016k BindingDB Entry DOI: 10.7270/Q2VX0GK3
Institute for Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 1 (Homo sapiens (Human))	BDBM50303174 (2-(5-((3-(4-(2-fluorobenzyloxy)phenyl)-1-phenyl-1H...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of recombinant Cdc25a				J Med Chem 52: 6716-23 (2009) Article DOI: 10.1021/jm901016k BindingDB Entry DOI: 10.7270/Q2VX0GK3
Institute for Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 3 (Homo sapiens (Human))	BDBM50303174 (2-(5-((3-(4-(2-fluorobenzyloxy)phenyl)-1-phenyl-1H...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of recombinant vaccina H1-related phosphatase				J Med Chem 52: 6716-23 (2009) Article DOI: 10.1021/jm901016k BindingDB Entry DOI: 10.7270/Q2VX0GK3
Institute for Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 1 (Homo sapiens (Human))	BDBM50303174 (2-(5-((3-(4-(2-fluorobenzyloxy)phenyl)-1-phenyl-1H...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of recombinant MKP1				J Med Chem 52: 6716-23 (2009) Article DOI: 10.1021/jm901016k BindingDB Entry DOI: 10.7270/Q2VX0GK3
Institute for Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair