null

SMILES: CC(C)Cc1cc(no1)C(=O)Nc1cc(C)on1

InChI Key: InChIKey=ARUFARLPAYCTLL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303398   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cruzipain (Trypanosoma cruzi)	BDBM50303398 (5-isobutyl-N-(5-methylisoxazol-3-yl)isoxazole-3-ca...) Show SMILES CC(C)Cc1cc(no1)C(=O)Nc1cc(C)on1 Show InChI InChI=1S/C12H15N3O3/c1-7(2)4-9-6-10(14-18-9)12(16)13-11-5-8(3)17-15-11/h5-7H,4H2,1-3H3,(H,13,15,16)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Tryapanosom cruzi cruzain by Flexstation microplate spectrofluorometry				J Med Chem 53: 37-51 (2010) Article DOI: 10.1021/jm901070c BindingDB Entry DOI: 10.7270/Q2ZP466W
					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50303398 (5-isobutyl-N-(5-methylisoxazol-3-yl)isoxazole-3-ca...) Show SMILES CC(C)Cc1cc(no1)C(=O)Nc1cc(C)on1 Show InChI InChI=1S/C12H15N3O3/c1-7(2)4-9-6-10(14-18-9)12(16)13-11-5-8(3)17-15-11/h5-7H,4H2,1-3H3,(H,13,15,16)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Tryapanosom cruzi cruzain by quantitative high throughput screening				J Med Chem 53: 37-51 (2010) Article DOI: 10.1021/jm901070c BindingDB Entry DOI: 10.7270/Q2ZP466W
					More data for this Ligand-Target Pair