BDBM50303537 CHEMBL570877::Methyl 3-(3-(2,2,3,3-Tetramethylcyclopropanecarbonyl)-1Hindol-1-yl)propanoate

SMILES: COC(=O)CCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12

InChI Key: InChIKey=ANOMNNUJQGKDNX-UHFFFAOYSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50303537   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50303537 (CHEMBL570877 | Methyl 3-(3-(2,2,3,3-Tetramethylcyc...) Show SMILES COC(=O)CCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12 Show InChI InChI=1S/C20H25NO3/c1-19(2)18(20(19,3)4)17(23)14-12-21(11-10-16(22)24-5)15-9-7-6-8-13(14)15/h6-9,12,18H,10-11H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells				J Med Chem 53: 295-315 (2010) Article DOI: 10.1021/jm901214q BindingDB Entry DOI: 10.7270/Q2KD1Z00
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50303537 (CHEMBL570877 | Methyl 3-(3-(2,2,3,3-Tetramethylcyc...) Show SMILES COC(=O)CCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12 Show InChI InChI=1S/C20H25NO3/c1-19(2)18(20(19,3)4)17(23)14-12-21(11-10-16(22)24-5)15-9-7-6-8-13(14)15/h6-9,12,18H,10-11H2,1-5H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.83E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells				J Med Chem 53: 295-315 (2010) Article DOI: 10.1021/jm901214q BindingDB Entry DOI: 10.7270/Q2KD1Z00
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50303537 (CHEMBL570877 | Methyl 3-(3-(2,2,3,3-Tetramethylcyc...) Show SMILES COC(=O)CCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12 Show InChI InChI=1S/C20H25NO3/c1-19(2)18(20(19,3)4)17(23)14-12-21(11-10-16(22)24-5)15-9-7-6-8-13(14)15/h6-9,12,18H,10-11H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay				J Med Chem 53: 295-315 (2010) Article DOI: 10.1021/jm901214q BindingDB Entry DOI: 10.7270/Q2KD1Z00
					More data for this Ligand-Target Pair