BDBM50303576 CHEMBL583473::[1-(2-Morpholin-4-ylethyl)-1H-indol-3-yl](3-noradamantane)-methanone

SMILES: O=C(c1cn(CCN2CCOCC2)c2ccccc12)C12CC3CC1CC(C2)C3

InChI Key: InChIKey=FLEORYUEILNRHW-UHFFFAOYSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50303576   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50303576 (CHEMBL583473 | [1-(2-Morpholin-4-ylethyl)-1H-indol...) Show SMILES O=C(c1cn(CCN2CCOCC2)c2ccccc12)C12CC3CC1CC(C2)C3 |TLB:22:21:26:23.24,22:23:20.21.27:26| Show InChI InChI=1S/C24H30N2O2/c27-23(24-14-17-11-18(15-24)13-19(24)12-17)21-16-26(22-4-2-1-3-20(21)22)6-5-25-7-9-28-10-8-25/h1-4,16-19H,5-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells				J Med Chem 53: 295-315 (2010) Article DOI: 10.1021/jm901214q BindingDB Entry DOI: 10.7270/Q2KD1Z00
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50303576 (CHEMBL583473 | [1-(2-Morpholin-4-ylethyl)-1H-indol...) Show SMILES O=C(c1cn(CCN2CCOCC2)c2ccccc12)C12CC3CC1CC(C2)C3 |TLB:22:21:26:23.24,22:23:20.21.27:26| Show InChI InChI=1S/C24H30N2O2/c27-23(24-14-17-11-18(15-24)13-19(24)12-17)21-16-26(22-4-2-1-3-20(21)22)6-5-25-7-9-28-10-8-25/h1-4,16-19H,5-15H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells				J Med Chem 53: 295-315 (2010) Article DOI: 10.1021/jm901214q BindingDB Entry DOI: 10.7270/Q2KD1Z00
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50303576 (CHEMBL583473 | [1-(2-Morpholin-4-ylethyl)-1H-indol...) Show SMILES O=C(c1cn(CCN2CCOCC2)c2ccccc12)C12CC3CC1CC(C2)C3 |TLB:22:21:26:23.24,22:23:20.21.27:26| Show InChI InChI=1S/C24H30N2O2/c27-23(24-14-17-11-18(15-24)13-19(24)12-17)21-16-26(22-4-2-1-3-20(21)22)6-5-25-7-9-28-10-8-25/h1-4,16-19H,5-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	68	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay				J Med Chem 53: 295-315 (2010) Article DOI: 10.1021/jm901214q BindingDB Entry DOI: 10.7270/Q2KD1Z00
					More data for this Ligand-Target Pair