BDBM50303596 CHEMBL566100::N-(4-(3-(3-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)ureido)phenylamino)quinolin-6-yl)propionamide

SMILES: CCC(=O)Nc1ccc2nccc(Nc3cccc(NC(=O)Nc4cc(nn4-c4ccc(C)cc4)C(C)(C)C)c3)c2c1

InChI Key: InChIKey=NOYDIAJXEFJPNS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303596   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50303596 (CHEMBL566100 | N-(4-(3-(3-(3-tert-butyl-1-p-tolyl-...) Show SMILES CCC(=O)Nc1ccc2nccc(Nc3cccc(NC(=O)Nc4cc(nn4-c4ccc(C)cc4)C(C)(C)C)c3)c2c1 Show InChI InChI=1S/C33H35N7O2/c1-6-31(41)36-24-12-15-27-26(19-24)28(16-17-34-27)35-22-8-7-9-23(18-22)37-32(42)38-30-20-29(33(3,4)5)39-40(30)25-13-10-21(2)11-14-25/h7-20H,6H2,1-5H3,(H,34,35)(H,36,41)(H2,37,38,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Genomics Centre of the Max Planck Society Curated by ChEMBL					Assay Description Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...				J Med Chem 53: 357-67 (2010) Article DOI: 10.1021/jm901297e BindingDB Entry DOI: 10.7270/Q29W0FKC
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50303596 (CHEMBL566100 | N-(4-(3-(3-(3-tert-butyl-1-p-tolyl-...) Show SMILES CCC(=O)Nc1ccc2nccc(Nc3cccc(NC(=O)Nc4cc(nn4-c4ccc(C)cc4)C(C)(C)C)c3)c2c1 Show InChI InChI=1S/C33H35N7O2/c1-6-31(41)36-24-12-15-27-26(19-24)28(16-17-34-27)35-22-8-7-9-23(18-22)37-32(42)38-30-20-29(33(3,4)5)39-40(30)25-13-10-21(2)11-14-25/h7-20H,6H2,1-5H3,(H,34,35)(H,36,41)(H2,37,38,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Genomics Centre of the Max Planck Society Curated by ChEMBL					Assay Description Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assay				J Med Chem 53: 357-67 (2010) Article DOI: 10.1021/jm901297e BindingDB Entry DOI: 10.7270/Q29W0FKC
					More data for this Ligand-Target Pair