BDBM50303673 CHEMBL567484::Thiophene-2-sulfonic acid{(E)-3-[1-(naphthalene-2-sulfonyl)-2,3-dihyd ro-1H-indol-7-yl]-acryloyl}-amide

SMILES: O=C(NS(=O)(=O)c1cccs1)\C=C\c1cccc2CCN(c12)S(=O)(=O)c1ccc2ccccc2c1

InChI Key: InChIKey=ZMMBWYWEVQMARK-ACCUITESSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303673   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50303673 (CHEMBL567484 | Thiophene-2-sulfonic acid{(E)-3-[1-...) Show SMILES O=C(NS(=O)(=O)c1cccs1)\C=C\c1cccc2CCN(c12)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C25H20N2O5S3/c28-23(26-34(29,30)24-9-4-16-33-24)13-11-19-7-3-8-20-14-15-27(25(19)20)35(31,32)22-12-10-18-5-1-2-6-21(18)17-22/h1-13,16-17H,14-15H2,(H,26,28)/b13-11+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting				J Med Chem 53: 18-36 (2010) Article DOI: 10.1021/jm9005912 BindingDB Entry DOI: 10.7270/Q2XP752H
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50303673 (CHEMBL567484 | Thiophene-2-sulfonic acid{(E)-3-[1-...) Show SMILES O=C(NS(=O)(=O)c1cccs1)\C=C\c1cccc2CCN(c12)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C25H20N2O5S3/c28-23(26-34(29,30)24-9-4-16-33-24)13-11-19-7-3-8-20-14-15-27(25(19)20)35(31,32)22-12-10-18-5-1-2-6-21(18)17-22/h1-13,16-17H,14-15H2,(H,26,28)/b13-11+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serum				J Med Chem 53: 18-36 (2010) Article DOI: 10.1021/jm9005912 BindingDB Entry DOI: 10.7270/Q2XP752H
					More data for this Ligand-Target Pair