BDBM50303901 1,4-Dihydroxynaphthalene::1,4-Naphthohydroquinone::1,4-naphthalenediol::CHEMBL206816::Naphthalene-1,4-diol

SMILES: Oc1ccc(O)c2ccccc12

InChI Key: InChIKey=PCILLCXFKWDRMK-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50303901   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50303901 (1,4-Dihydroxynaphthalene | 1,4-Naphthohydroquinone...) Show SMILES Oc1ccc(O)c2ccccc12 Show InChI InChI=1S/C10H8O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,11-12H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO expressed in HEK293 cells assessed as blockade of tryptophan degradation by HPLC				J Med Chem 53: 1172-89 (2010) Article DOI: 10.1021/jm9014718 BindingDB Entry DOI: 10.7270/Q2BC40G9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50303901 (1,4-Dihydroxynaphthalene | 1,4-Naphthohydroquinone...) Show SMILES Oc1ccc(O)c2ccccc12 Show InChI InChI=1S/C10H8O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,11-12H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of mouse recombinant IDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLC				J Med Chem 53: 1172-89 (2010) Article DOI: 10.1021/jm9014718 BindingDB Entry DOI: 10.7270/Q2BC40G9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50303901 (1,4-Dihydroxynaphthalene | 1,4-Naphthohydroquinone...) Show SMILES Oc1ccc(O)c2ccccc12 Show InChI InChI=1S/C10H8O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,11-12H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AI				J Med Chem 53: 1172-89 (2010) Article DOI: 10.1021/jm9014718 BindingDB Entry DOI: 10.7270/Q2BC40G9
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Mus musculus)	BDBM50303901 (1,4-Dihydroxynaphthalene | 1,4-Naphthohydroquinone...) Show SMILES Oc1ccc(O)c2ccccc12 Show InChI InChI=1S/C10H8O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,11-12H	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of mouse recombinant TDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLC				J Med Chem 53: 1172-89 (2010) Article DOI: 10.1021/jm9014718 BindingDB Entry DOI: 10.7270/Q2BC40G9
					More data for this Ligand-Target Pair