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SMILES: CC(C)Nc1cc(ccn1)-c1nc2cccnc2nc1-c1ccc(F)cc1

InChI Key: InChIKey=WFYZCSNCAWYAKG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304008   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50304008
PNG
(3-(4-Fluorophenyl)-2-(2-isopropylaminopyridin-4-yl...)
Show SMILES CC(C)Nc1cc(ccn1)-c1nc2cccnc2nc1-c1ccc(F)cc1
Show InChI InChI=1S/C21H18FN5/c1-13(2)25-18-12-15(9-11-23-18)20-19(14-5-7-16(22)8-6-14)27-21-17(26-20)4-3-10-24-21/h3-13H,1-2H3,(H,23,25)
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Article
PubMed
n/an/a 38n/an/an/an/an/an/a



Eberhard-Karls-University of T£bingen

Curated by ChEMBL


Assay Description
Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATP

J Med Chem 53: 1128-37 (2010)


Article DOI: 10.1021/jm901392x
BindingDB Entry DOI: 10.7270/Q2CR5TF8
More data for this
Ligand-Target Pair