BDBM50304110 (Z)-5'-Amino-1H,1'H-[2,3']biindolylidene-3,2'-dione::5'-Amino-1H,1'H-[2,3']biindolylidene-3,2'-dione::CHEMBL594192

SMILES: Nc1ccc2NC(=O)C(=C3Nc4ccccc4C3=O)c2c1

InChI Key: InChIKey=UKVQMBJHWHGXOI-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50304110   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase 17B (STK17B) (Homo sapiens (Human))	BDBM50304110 ((Z)-5'-Amino-1H,1'H-[2,3']biindolylidene-3,2'-dion...) Show SMILES Nc1ccc2NC(=O)C(=C3Nc4ccccc4C3=O)c2c1 |w:9.18| Show InChI InChI=1S/C16H11N3O2/c17-8-5-6-12-10(7-8)13(16(21)19-12)14-15(20)9-3-1-2-4-11(9)18-14/h1-7,18H,17H2,(H,19,21)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of DRAK2 (unknown origin) using MRLC3 peptide as substrate incubated for 2 hrs by ADP-Glo kinase assay				Bioorg Med Chem Lett 26: 2719-23 (2016) Article DOI: 10.1016/j.bmcl.2016.03.111 BindingDB Entry DOI: 10.7270/Q2N29ZTZ
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50304110 ((Z)-5'-Amino-1H,1'H-[2,3']biindolylidene-3,2'-dion...) Show SMILES Nc1ccc2NC(=O)C(=C3Nc4ccccc4C3=O)c2c1 |w:9.18| Show InChI InChI=1S/C16H11N3O2/c17-8-5-6-12-10(7-8)13(16(21)19-12)14-15(20)9-3-1-2-4-11(9)18-14/h1-7,18H,17H2,(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	359	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of FLT3 by HTRF assay				Bioorg Med Chem Lett 20: 2033-7 (2010) Article DOI: 10.1016/j.bmcl.2010.01.039 BindingDB Entry DOI: 10.7270/Q29W0GF0
					More data for this Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5) (Homo sapiens (Human))	BDBM50304110 ((Z)-5'-Amino-1H,1'H-[2,3']biindolylidene-3,2'-dion...) Show SMILES Nc1ccc2NC(=O)C(=C3Nc4ccccc4C3=O)c2c1 |w:9.18| Show InChI InChI=1S/C16H11N3O2/c17-8-5-6-12-10(7-8)13(16(21)19-12)14-15(20)9-3-1-2-4-11(9)18-14/h1-7,18H,17H2,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de La Rochelle Curated by ChEMBL					Assay Description Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation counting				Bioorg Med Chem 17: 6257-63 (2009) Article DOI: 10.1016/j.bmc.2009.07.051 BindingDB Entry DOI: 10.7270/Q2BR8S9W
					More data for this Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (RAT)	BDBM50304110 ((Z)-5'-Amino-1H,1'H-[2,3']biindolylidene-3,2'-dion...) Show SMILES Nc1ccc2NC(=O)C(=C3Nc4ccccc4C3=O)c2c1 |w:9.18| Show InChI InChI=1S/C16H11N3O2/c17-8-5-6-12-10(7-8)13(16(21)19-12)14-15(20)9-3-1-2-4-11(9)18-14/h1-7,18H,17H2,(H,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de La Rochelle Curated by ChEMBL					Assay Description Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...				Bioorg Med Chem 17: 6257-63 (2009) Article DOI: 10.1016/j.bmc.2009.07.051 BindingDB Entry DOI: 10.7270/Q2BR8S9W
					More data for this Ligand-Target Pair