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SMILES: [#8]-[#6](=O)-[#6@@H]-1-[#6]-[#6@@H](F)-[#6]-[#7]-1-[#6]-[#6]\[#6]=[#6](\c1ccccc1)-c1ccccc1

InChI Key: InChIKey=BNOWYSCFNGUYGZ-QUCCMNQESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304274   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium- and chloride-dependent GABA transporter 1


(Mus musculus)		BDBM50304274
PNG
((2S,4R)-1-(4,4-diphenyl-3-butenyl)-4-fluoropyrroli...)
Show SMILES [#8]-[#6](=O)-[#6@@H]-1-[#6]-[#6@@H](F)-[#6]-[#7]-1-[#6]-[#6]\[#6]=[#6](\c1ccccc1)-c1ccccc1 |r|
Show InChI InChI=1S/C21H22FNO2/c22-18-14-20(21(24)25)23(15-18)13-7-12-19(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-12,18,20H,7,13-15H2,(H,24,25)/t18-,20+/m1/s1
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Similars
Article
PubMed
n/an/a 6.74E+4n/an/an/an/an/an/a



Institute of Microbiology

Curated by ChEMBL


Assay Description
Inhibition of GAT1 in mouse D8 cells assessed as [3H]GABA transport by liquid scintillation counting

Bioorg Med Chem 17: 6540-6 (2009)


Article DOI: 10.1016/j.bmc.2009.08.010
BindingDB Entry DOI: 10.7270/Q26110DK
More data for this
Ligand-Target Pair