null

SMILES: O=C(Nc1cnn(c1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ncccc21

InChI Key: InChIKey=CHVWLHQBPZRRKI-VVONHTQRSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304298   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50304298 (CHEMBL595120 | trans-3-Oxo-N-(1-phenyl-1H-pyrazol-...) Show SMILES O=C(Nc1cnn(c1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ncccc21 |r,wU:17.22,wD:14.15,(-4.96,-20.66,;-4.19,-21.99,;-2.65,-21.99,;-1.77,-23.26,;-.23,-23.29,;.22,-24.77,;-1.05,-25.64,;-2.28,-24.71,;-1.08,-27.17,;-2.44,-27.91,;-2.47,-29.45,;-1.16,-30.25,;.2,-29.51,;.23,-27.97,;-4.96,-23.32,;-6.5,-23.32,;-7.28,-24.66,;-6.5,-25.99,;-4.96,-25.99,;-4.2,-24.66,;-5.58,-27.24,;-6.49,-28.5,;-6.02,-29.96,;-7.97,-28.02,;-9.3,-28.79,;-10.64,-28.02,;-10.63,-26.48,;-9.31,-25.7,;-7.97,-26.47,)| Show InChI InChI=1S/C22H20N4O3/c27-20(25-16-13-24-26(14-16)17-5-2-1-3-6-17)15-8-10-22(11-9-15)18-7-4-12-23-19(18)21(28)29-22/h1-7,12-15H,8-11H2,(H,25,27)/t15-,22-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Rat 6B)	BDBM50304298 (CHEMBL595120 | trans-3-Oxo-N-(1-phenyl-1H-pyrazol-...) Show SMILES O=C(Nc1cnn(c1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ncccc21 |r,wU:17.22,wD:14.15,(-4.96,-20.66,;-4.19,-21.99,;-2.65,-21.99,;-1.77,-23.26,;-.23,-23.29,;.22,-24.77,;-1.05,-25.64,;-2.28,-24.71,;-1.08,-27.17,;-2.44,-27.91,;-2.47,-29.45,;-1.16,-30.25,;.2,-29.51,;.23,-27.97,;-4.96,-23.32,;-6.5,-23.32,;-7.28,-24.66,;-6.5,-25.99,;-4.96,-25.99,;-4.2,-24.66,;-5.58,-27.24,;-6.49,-28.5,;-6.02,-29.96,;-7.97,-28.02,;-9.3,-28.79,;-10.64,-28.02,;-10.63,-26.48,;-9.31,-25.7,;-7.97,-26.47,)| Show InChI InChI=1S/C22H20N4O3/c27-20(25-16-13-24-26(14-16)17-5-2-1-3-6-17)15-8-10-22(11-9-15)18-7-4-12-23-19(18)21(28)29-22/h1-7,12-15H,8-11H2,(H,25,27)/t15-,22-	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of rat Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair