BDBM50304299 CHEMBL595560::trans-3-Oxo-N-(1-phenyl-1H-pyrazol-3-yl)-3H-spiro[6-aza-2-benzofuran-1,1'-cyclohexane]-4'-carboxamide

SMILES: O=C(Nc1ccn(n1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21

InChI Key: InChIKey=RVLHZDSBPUFJHK-VVONHTQRSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304299   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50304299 (CHEMBL595560 | trans-3-Oxo-N-(1-phenyl-1H-pyrazol-...) Show SMILES O=C(Nc1ccn(n1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21 |r,wU:17.22,wD:14.15,(12.31,-8.24,;13.08,-9.57,;14.62,-9.57,;15.45,-10.87,;16.99,-10.95,;17.38,-12.44,;16.09,-13.28,;14.9,-12.31,;16.01,-14.82,;14.63,-15.51,;14.55,-17.04,;15.84,-17.89,;17.22,-17.18,;17.3,-15.65,;12.3,-10.9,;10.76,-10.9,;9.99,-12.24,;10.76,-13.56,;12.3,-13.56,;13.07,-12.24,;11.68,-14.82,;10.77,-16.08,;11.25,-17.54,;9.3,-15.6,;7.96,-16.37,;6.63,-15.6,;6.63,-14.05,;7.96,-13.28,;9.3,-14.05,)| Show InChI InChI=1S/C22H20N4O3/c27-20(24-19-9-13-26(25-19)16-4-2-1-3-5-16)15-6-10-22(11-7-15)18-14-23-12-8-17(18)21(28)29-22/h1-5,8-9,12-15H,6-7,10-11H2,(H,24,25,27)/t15-,22-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Rat 6B)	BDBM50304299 (CHEMBL595560 | trans-3-Oxo-N-(1-phenyl-1H-pyrazol-...) Show SMILES O=C(Nc1ccn(n1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21 |r,wU:17.22,wD:14.15,(12.31,-8.24,;13.08,-9.57,;14.62,-9.57,;15.45,-10.87,;16.99,-10.95,;17.38,-12.44,;16.09,-13.28,;14.9,-12.31,;16.01,-14.82,;14.63,-15.51,;14.55,-17.04,;15.84,-17.89,;17.22,-17.18,;17.3,-15.65,;12.3,-10.9,;10.76,-10.9,;9.99,-12.24,;10.76,-13.56,;12.3,-13.56,;13.07,-12.24,;11.68,-14.82,;10.77,-16.08,;11.25,-17.54,;9.3,-15.6,;7.96,-16.37,;6.63,-15.6,;6.63,-14.05,;7.96,-13.28,;9.3,-14.05,)| Show InChI InChI=1S/C22H20N4O3/c27-20(24-19-9-13-26(25-19)16-4-2-1-3-5-16)15-6-10-22(11-7-15)18-14-23-12-8-17(18)21(28)29-22/h1-5,8-9,12-15H,6-7,10-11H2,(H,24,25,27)/t15-,22-	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of rat Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair