BDBM50304303 CHEMBL593934::trans-3-Oxo-N-(5-phenylpyrazin-2-yl)-3H-spiro[2-benzofuran-1,1'-cyclohexane]-4'-carboxamide

SMILES: O=C(Nc1cnc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccccc21

InChI Key: InChIKey=PAKZAKJEQWGGBZ-WVQHILGCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304303   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50304303 (CHEMBL593934 | trans-3-Oxo-N-(5-phenylpyrazin-2-yl...) Show SMILES O=C(Nc1cnc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccccc21 |r,wU:18.23,wD:15.16,(-4.29,5.75,;-3.52,4.41,;-1.98,4.41,;-1.21,3.08,;-1.99,1.75,;-1.22,.41,;.32,.41,;1.09,1.75,;.32,3.08,;1.09,-.92,;.32,-2.25,;1.08,-3.58,;2.63,-3.58,;3.4,-2.24,;2.62,-.91,;-4.29,3.08,;-5.83,3.08,;-6.61,1.75,;-5.83,.42,;-4.29,.42,;-3.53,1.75,;-4.91,-.84,;-5.83,-2.09,;-5.35,-3.56,;-7.3,-1.61,;-8.63,-2.39,;-9.97,-1.61,;-9.97,-.07,;-8.64,.7,;-7.3,-.06,)| Show InChI InChI=1S/C24H21N3O3/c28-22(27-21-15-25-20(14-26-21)16-6-2-1-3-7-16)17-10-12-24(13-11-17)19-9-5-4-8-18(19)23(29)30-24/h1-9,14-15,17H,10-13H2,(H,26,27,28)/t17-,24-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair