BDBM50304305 CHEMBL607192::trans-3-Oxo-N-(5-phenylisoxazol-3-yl)-3H-spiro[4-aza-2-benzofuran-1,1'-cyclohexane]-4'-carboxamide

SMILES: O=C(Nc1cc(on1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ncccc21

InChI Key: InChIKey=ANXRLCSDKKYMPM-VVONHTQRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304305   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50304305 (CHEMBL607192 | trans-3-Oxo-N-(5-phenylisoxazol-3-y...) Show SMILES O=C(Nc1cc(on1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ncccc21 |r,wU:17.22,wD:14.15,(-4.45,-8.24,;-3.68,-9.57,;-2.14,-9.57,;-1.26,-10.84,;-1.77,-12.3,;-.55,-13.24,;.72,-12.36,;.28,-10.88,;-.58,-14.78,;-1.93,-15.51,;-1.97,-17.04,;-.65,-17.85,;.7,-17.1,;.73,-15.56,;-4.45,-10.9,;-5.99,-10.9,;-6.76,-12.24,;-5.99,-13.56,;-4.45,-13.56,;-3.68,-12.24,;-5.07,-14.82,;-5.98,-16.08,;-5.51,-17.54,;-7.46,-15.6,;-8.79,-16.37,;-10.12,-15.6,;-10.12,-14.05,;-8.79,-13.28,;-7.46,-14.05,)| Show InChI InChI=1S/C22H19N3O4/c26-20(24-18-13-17(29-25-18)14-5-2-1-3-6-14)15-8-10-22(11-9-15)16-7-4-12-23-19(16)21(27)28-22/h1-7,12-13,15H,8-11H2,(H,24,25,26)/t15-,22-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair