BDBM50304307 CHEMBL595121::trans-3-Oxo-N-(5-phenylpyrazin-2-yl)-3H-spiro[5-aza-2-benzofuran-1,1'-cyclohexane]-4'-carboxamide

SMILES: O=C(Nc1cnc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1cnccc21

InChI Key: InChIKey=IKNKRWFBAPZVTP-QXONSOMPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304307   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50304307 (CHEMBL595121 | trans-3-Oxo-N-(5-phenylpyrazin-2-yl...) Show SMILES O=C(Nc1cnc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1cnccc21 |r,wU:18.23,wD:15.16,(10.15,-23,;10.91,-24.33,;12.45,-24.34,;13.29,-25.63,;12.58,-26.99,;13.42,-28.29,;14.96,-28.21,;15.66,-26.83,;14.82,-25.54,;15.8,-29.5,;15.09,-30.87,;15.93,-32.16,;17.47,-32.09,;18.17,-30.71,;17.33,-29.42,;10.14,-25.67,;8.6,-25.67,;7.83,-27,;8.6,-28.33,;10.14,-28.33,;10.91,-27,;9.52,-29.58,;8.61,-30.84,;9.09,-32.3,;7.13,-30.36,;5.8,-31.13,;4.47,-30.36,;4.47,-28.82,;5.8,-28.05,;7.13,-28.81,)| Show InChI InChI=1S/C23H20N4O3/c28-21(27-20-14-25-19(13-26-20)15-4-2-1-3-5-15)16-6-9-23(10-7-16)18-8-11-24-12-17(18)22(29)30-23/h1-5,8,11-14,16H,6-7,9-10H2,(H,26,27,28)/t16-,23-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair