BDBM50304309 CHEMBL607144::trans-3-Oxo-N-(5-phenylpyrazin-2-yl)-3H-spiro[6-aza-2-benzofuran-1,1'-cyclohexane]-4'-carboxamide

SMILES: O=C(Nc1cnc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21

InChI Key: InChIKey=PFQMQZUBTCVKMM-QXONSOMPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304309   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50304309 (CHEMBL607144 | trans-3-Oxo-N-(5-phenylpyrazin-2-yl...) Show SMILES O=C(Nc1cnc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21 |r,wU:18.23,wD:15.16,(12.25,-35.6,;13.01,-36.93,;14.55,-36.94,;15.39,-38.23,;14.68,-39.59,;15.52,-40.89,;17.06,-40.81,;17.76,-39.43,;16.92,-38.14,;17.9,-42.1,;17.19,-43.47,;18.03,-44.76,;19.57,-44.69,;20.27,-43.31,;19.43,-42.02,;12.24,-38.27,;10.7,-38.27,;9.93,-39.6,;10.7,-40.93,;12.24,-40.93,;13.01,-39.6,;11.62,-42.18,;10.71,-43.44,;11.19,-44.9,;9.23,-42.96,;7.9,-43.73,;6.57,-42.96,;6.57,-41.42,;7.9,-40.65,;9.23,-41.41,)| Show InChI InChI=1S/C23H20N4O3/c28-21(27-20-14-25-19(13-26-20)15-4-2-1-3-5-15)16-6-9-23(10-7-16)18-12-24-11-8-17(18)22(29)30-23/h1-5,8,11-14,16H,6-7,9-10H2,(H,26,27,28)/t16-,23-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair