BDBM50304310 CHEMBL596264::trans-3-Oxo-N-(5-phenylisoxazol-3-yl)-3H-spiro[6-aza-2-benzofuran-1,1'-cyclohexane]-4'-carboxamide

SMILES: O=C(Nc1cc(on1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21

InChI Key: InChIKey=IVPSRSHZKXJNAW-VVONHTQRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304310   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50304310 (CHEMBL596264 | trans-3-Oxo-N-(5-phenylisoxazol-3-y...) Show SMILES O=C(Nc1cc(on1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21 |r,wU:17.22,wD:14.15,(-3.73,5.98,;-2.96,4.65,;-1.42,4.65,;-.52,3.4,;-1,1.93,;.24,1.03,;1.49,1.93,;1.01,3.39,;.24,-.51,;-1.1,-1.28,;-1.1,-2.82,;.23,-3.59,;1.57,-2.81,;1.57,-1.28,;-3.73,3.31,;-5.27,3.31,;-6.05,1.98,;-5.27,.65,;-3.73,.65,;-2.97,1.98,;-4.35,-.6,;-5.27,-1.86,;-4.79,-3.32,;-6.74,-1.38,;-8.07,-2.15,;-9.41,-1.38,;-9.41,.16,;-8.08,.93,;-6.74,.17,)| Show InChI InChI=1S/C22H19N3O4/c26-20(24-19-12-18(29-25-19)14-4-2-1-3-5-14)15-6-9-22(10-7-15)17-13-23-11-8-16(17)21(27)28-22/h1-5,8,11-13,15H,6-7,9-10H2,(H,24,25,26)/t15-,22-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair