BDBM50304313 CHEMBL607037::trans-3-Oxo-N-(2-phenyl-1,3-thiazol-4-yl)-3H-spiro[6-aza-2-benzofuran-1,1'-cyclohexane]-4'-carboxamide

SMILES: O=C(Nc1csc(n1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21

InChI Key: InChIKey=OYYWUJLGWLCFON-CAJLXGCNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304313   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50304313 (CHEMBL607037 | trans-3-Oxo-N-(2-phenyl-1,3-thiazol...) Show SMILES O=C(Nc1csc(n1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccncc21 |r,wU:17.22,wD:14.15,(-3.64,-7.7,;-2.87,-9.03,;-1.33,-9.04,;-.39,-10.26,;1.15,-10.22,;1.66,-11.67,;.44,-12.61,;-.83,-11.74,;.48,-14.15,;-.83,-14.95,;-.79,-16.49,;.56,-17.22,;1.88,-16.41,;1.83,-14.88,;-3.64,-10.37,;-5.18,-10.37,;-5.95,-11.7,;-5.18,-13.03,;-3.64,-13.03,;-2.87,-11.7,;-4.26,-14.29,;-5.17,-15.54,;-4.7,-17.01,;-6.65,-15.06,;-7.98,-15.83,;-9.31,-15.06,;-9.31,-13.52,;-7.98,-12.75,;-6.65,-13.51,)| Show InChI InChI=1S/C22H19N3O3S/c26-19(24-18-13-29-20(25-18)15-4-2-1-3-5-15)14-6-9-22(10-7-14)17-12-23-11-8-16(17)21(27)28-22/h1-5,8,11-14H,6-7,9-10H2,(H,24,26)/t14-,22-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair