BDBM50304317 CHEMBL593466::trans-3-Oxo-N-(5-phenylpyrazin-2-yl)-3H-spiro[7-aza-2-benzofuran-1,1'-cyclohexane]-4'-carboxamide

SMILES: O=C(Nc1cnc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1cccnc21

InChI Key: InChIKey=AYRAARHLSBTZKB-QXONSOMPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50304317 (CHEMBL593466 | trans-3-Oxo-N-(5-phenylpyrazin-2-yl...) Show SMILES O=C(Nc1cnc(cn1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1cccnc21 |r,wU:18.23,wD:15.16,(11.21,-36.61,;11.98,-37.94,;13.52,-37.95,;14.33,-39.26,;13.59,-40.61,;14.41,-41.92,;15.95,-41.87,;16.67,-40.5,;15.86,-39.2,;16.76,-43.17,;16.03,-44.53,;16.84,-45.84,;18.38,-45.79,;19.11,-44.42,;18.29,-43.12,;11.21,-39.28,;9.67,-39.28,;8.89,-40.61,;9.67,-41.94,;11.21,-41.94,;11.97,-40.61,;10.59,-43.2,;9.68,-44.45,;10.15,-45.92,;8.2,-43.97,;6.87,-44.74,;5.53,-43.97,;5.54,-42.43,;6.86,-41.66,;8.2,-42.42,)| Show InChI InChI=1S/C23H20N4O3/c28-21(27-19-14-25-18(13-26-19)15-5-2-1-3-6-15)16-8-10-23(11-9-16)20-17(22(29)30-23)7-4-12-24-20/h1-7,12-14,16H,8-11H2,(H,26,27,28)/t16-,23-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair