BDBM50304318 CHEMBL594888::trans-3-Oxo-N-(5-phenylisoxazol-3-yl)-3H-spiro[7-aza-2-benzofuran-1,1'-cyclohexane]-4'-carboxamide

SMILES: O=C(Nc1cc(on1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1cccnc21

InChI Key: InChIKey=RLCDWIQGBPVXHB-VVONHTQRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304318   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50304318 (CHEMBL594888 | trans-3-Oxo-N-(5-phenylisoxazol-3-y...) Show SMILES O=C(Nc1cc(on1)-c1ccccc1)[C@H]1CC[C@@]2(CC1)OC(=O)c1cccnc21 |r,wU:17.22,wD:14.15,(-2.39,3.57,;-1.62,2.24,;-.08,2.23,;.84,1,;.38,-.47,;1.64,-1.36,;2.87,-.43,;2.37,1.02,;1.67,-2.89,;.34,-3.68,;.36,-5.22,;1.71,-5.97,;3.04,-5.17,;3.01,-3.63,;-2.4,.9,;-3.94,.9,;-4.71,-.43,;-3.94,-1.76,;-2.4,-1.76,;-1.63,-.43,;-3.02,-3.02,;-3.93,-4.27,;-3.45,-5.74,;-5.4,-3.79,;-6.74,-4.56,;-8.07,-3.79,;-8.07,-2.25,;-6.74,-1.48,;-5.4,-2.24,)| Show InChI InChI=1S/C22H19N3O4/c26-20(24-18-13-17(29-25-18)14-5-2-1-3-6-14)15-8-10-22(11-9-15)19-16(21(27)28-22)7-4-12-23-19/h1-7,12-13,15H,8-11H2,(H,24,25,26)/t15-,22-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor				Bioorg Med Chem 17: 6971-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.019 BindingDB Entry DOI: 10.7270/Q2P26Z62
					More data for this Ligand-Target Pair