BDBM50304334 3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-tropane::CHEMBL593963

SMILES: CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cc2ccccc2n1C

InChI Key: InChIKey=WGAYVVNWRFPKMG-ZIAGYGMSSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50304334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin (5-HT) receptor (RAT)	BDBM50304334 (3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-tropane | ...) Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cc2ccccc2n1C |r,THB:9:7:1:3.4| Show InChI InChI=1S/C18H22N2O2/c1-19-13-7-8-14(19)11-15(10-13)22-18(21)17-9-12-5-3-4-6-16(12)20(17)2/h3-6,9,13-15H,7-8,10-11H2,1-2H3/t13-,14-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Hungarian Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]granisectron from 5HT3 receptor in Wistar rat forebrain				Bioorg Med Chem 17: 6872-8 (2009) Article DOI: 10.1016/j.bmc.2009.08.029 BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
					More data for this Ligand-Target Pair
Glycine, non-strychnine (RAT)	BDBM50304334 (3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-tropane | ...) Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cc2ccccc2n1C |r,THB:9:7:1:3.4| Show InChI InChI=1S/C18H22N2O2/c1-19-13-7-8-14(19)11-15(10-13)22-18(21)17-9-12-5-3-4-6-16(12)20(17)2/h3-6,9,13-15H,7-8,10-11H2,1-2H3/t13-,14-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hungarian Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry				Bioorg Med Chem 17: 6872-8 (2009) Article DOI: 10.1016/j.bmc.2009.08.029 BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
					More data for this Ligand-Target Pair
Glycine, non-strychnine (RAT)	BDBM50304334 (3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-tropane | ...) Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cc2ccccc2n1C |r,THB:9:7:1:3.4| Show InChI InChI=1S/C18H22N2O2/c1-19-13-7-8-14(19)11-15(10-13)22-18(21)17-9-12-5-3-4-6-16(12)20(17)2/h3-6,9,13-15H,7-8,10-11H2,1-2H3/t13-,14-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10.2	n/a	n/a	n/a	n/a	n/a	n/a
Hungarian Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry				Bioorg Med Chem 17: 6872-8 (2009) Article DOI: 10.1016/j.bmc.2009.08.029 BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
					More data for this Ligand-Target Pair
Glycine, non-strychnine (RAT)	BDBM50304334 (3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-tropane | ...) Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cc2ccccc2n1C |r,THB:9:7:1:3.4| Show InChI InChI=1S/C18H22N2O2/c1-19-13-7-8-14(19)11-15(10-13)22-18(21)17-9-12-5-3-4-6-16(12)20(17)2/h3-6,9,13-15H,7-8,10-11H2,1-2H3/t13-,14-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hungarian Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry				Bioorg Med Chem 17: 6872-8 (2009) Article DOI: 10.1016/j.bmc.2009.08.029 BindingDB Entry DOI: 10.7270/Q2DJ5FQJ
					More data for this Ligand-Target Pair