BDBM50304335 3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane::CHEMBL608710
SMILES: Cn1c(cc2ccccc12)C(=O)OC1C[C@H]2CC[C@H](C1)N2
InChI Key: InChIKey=CBUHKJLQRNBVRE-CHWSQXEVSA-N
Data: 7 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serotonin (5-HT) receptor (RAT) | BDBM50304335 (3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Hungarian Academy of Sciences Curated by ChEMBL | Assay Description Displacement of [3H]granisectron from 5HT3 receptor in Wistar rat forebrain | Bioorg Med Chem 17: 6872-8 (2009) Article DOI: 10.1016/j.bmc.2009.08.029 BindingDB Entry DOI: 10.7270/Q2DJ5FQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycine, non-strychnine (RAT) | BDBM50304335 (3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 33.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Hungarian Academy of Sciences Curated by ChEMBL | Assay Description Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry | Bioorg Med Chem 17: 6872-8 (2009) Article DOI: 10.1016/j.bmc.2009.08.029 BindingDB Entry DOI: 10.7270/Q2DJ5FQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycine, non-strychnine (RAT) | BDBM50304335 (3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hungarian Academy of Sciences Curated by ChEMBL | Assay Description Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry | Bioorg Med Chem 17: 6872-8 (2009) Article DOI: 10.1016/j.bmc.2009.08.029 BindingDB Entry DOI: 10.7270/Q2DJ5FQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycine, non-strychnine (RAT) | BDBM50304335 (3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 70.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Hungarian Academy of Sciences Curated by ChEMBL | Assay Description Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry in presence of 10 uM glycine | Bioorg Med Chem 17: 6872-8 (2009) Article DOI: 10.1016/j.bmc.2009.08.029 BindingDB Entry DOI: 10.7270/Q2DJ5FQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycine, non-strychnine (RAT) | BDBM50304335 (3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.07 | n/a | n/a | n/a | n/a | n/a | n/a |
Hungarian Academy of Sciences Curated by ChEMBL | Assay Description Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry in presence of 10 uM glycine | Bioorg Med Chem 17: 6872-8 (2009) Article DOI: 10.1016/j.bmc.2009.08.029 BindingDB Entry DOI: 10.7270/Q2DJ5FQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycine, non-strychnine (RAT) | BDBM50304335 (3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 135 | n/a | n/a | n/a | n/a | n/a | n/a |
Hungarian Academy of Sciences Curated by ChEMBL | Assay Description Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry in presence of 10 uM glycine | Bioorg Med Chem 17: 6872-8 (2009) Article DOI: 10.1016/j.bmc.2009.08.029 BindingDB Entry DOI: 10.7270/Q2DJ5FQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycine, non-strychnine (RAT) | BDBM50304335 (3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
Hungarian Academy of Sciences Curated by ChEMBL | Assay Description Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry | Bioorg Med Chem 17: 6872-8 (2009) Article DOI: 10.1016/j.bmc.2009.08.029 BindingDB Entry DOI: 10.7270/Q2DJ5FQJ | |||||||||||
More data for this Ligand-Target Pair |