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SMILES: NC(=O)c1c(N)sc2CN(Cc3ccccc3)CCc12

InChI Key: InChIKey=LGGWACZZAOTYKK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304472   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Adenosine receptor A1


(Homo sapiens (Human))		BDBM50304472
PNG
(2-Amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]py...)
Show SMILES NC(=O)c1c(N)sc2CN(Cc3ccccc3)CCc12
Show InChI InChI=1S/C15H17N3OS/c16-14(19)13-11-6-7-18(9-12(11)20-15(13)17)8-10-4-2-1-3-5-10/h1-5H,6-9,17H2,(H2,16,19)
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Article
PubMed
n/an/an/an/a>2.00E+4n/an/an/an/a



Monash University (Parkville Campus)

Curated by ChEMBL


Assay Description
Allosteric modulatory activity at human adenosine A1 receptor expressed in CHOk1 cells assessed as drug level causing half maximal allosteric effect ...

Bioorg Med Chem 17: 7353-61 (2009)


Article DOI: 10.1016/j.bmc.2009.08.024
BindingDB Entry DOI: 10.7270/Q2H9959W
More data for this
Ligand-Target Pair