BDBM50304586 (R,S)-N-[2-Benzoyl-4-[N-(phenylsulfonyl)phenyl-sulfamoyl]phenyl]-2-(4-methyl-piperazin-1-yl)-2-phenylacetamide::CHEMBL595996

SMILES: CN1CCN(CC1)C(C(=O)Nc1ccc(cc1C(=O)c1ccccc1)N(S(=O)(=O)c1ccccc1)S(=O)(=O)c1ccccc1)c1ccccc1

InChI Key: InChIKey=KCDLNXYAMQIANP-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304586   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P-glycoprotein 1 (Homo sapiens (Human))	BDBM50304586 ((R,S)-N-[2-Benzoyl-4-[N-(phenylsulfonyl)phenyl-sul...) Show SMILES CN1CCN(CC1)C(C(=O)Nc1ccc(cc1C(=O)c1ccccc1)N(S(=O)(=O)c1ccccc1)S(=O)(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C38H36N4O6S2/c1-40-24-26-41(27-25-40)36(29-14-6-2-7-15-29)38(44)39-35-23-22-31(28-34(35)37(43)30-16-8-3-9-17-30)42(49(45,46)32-18-10-4-11-19-32)50(47,48)33-20-12-5-13-21-33/h2-23,28,36H,24-27H2,1H3,(H,39,44)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
Philipps-Universit£t Marburg Curated by ChEMBL					Assay Description Inhibition of ABCB1 overexpressed in human CCRF-CEM/VCR1000 cell assessed as inhibition of daunomycin efflux after 30 mins by FACS analysis				Bioorg Med Chem 17: 7690-7 (2009) Article DOI: 10.1016/j.bmc.2009.09.043 BindingDB Entry DOI: 10.7270/Q2319W02
					More data for this Ligand-Target Pair