BDBM50304606 5-(4-(benzyloxy)phenyl)-1,3,4-oxadiazole-2(3H)-thione::5-[4-Benzyloxyphenyl]-1,3,4-oxadiazole-2(3H)-thione::CHEMBL607528
SMILES: Sc1nnc(o1)-c1ccc(OCc2ccccc2)cc1
InChI Key: InChIKey=DNJPRYZTAXMJSZ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosinase (Agaricus bisporus (Common mushroom)) | BDBM50304606 (5-(4-(benzyloxy)phenyl)-1,3,4-oxadiazole-2(3H)-thi...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University Curated by ChEMBL | Assay Description Inhibition of mashroom tyrosinase | Bioorg Med Chem 18: 4042-8 (2010) Article DOI: 10.1016/j.bmc.2010.04.021 BindingDB Entry DOI: 10.7270/Q2FJ2GZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Homo sapiens (Human)) | BDBM50304606 (5-(4-(benzyloxy)phenyl)-1,3,4-oxadiazole-2(3H)-thi...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Karachi Curated by ChEMBL | Assay Description Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysis | Bioorg Med Chem 17: 7816-22 (2009) Article DOI: 10.1016/j.bmc.2009.09.011 BindingDB Entry DOI: 10.7270/Q2ZC82X2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Homo sapiens (Human)) | BDBM50304606 (5-(4-(benzyloxy)phenyl)-1,3,4-oxadiazole-2(3H)-thi...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.28E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Karachi Curated by ChEMBL | Assay Description Inhibition of human recombinant NPP1 assessed as release of p-nitrophenol by microtitre plate spectrophotometry | Bioorg Med Chem 17: 7816-22 (2009) Article DOI: 10.1016/j.bmc.2009.09.011 BindingDB Entry DOI: 10.7270/Q2ZC82X2 | |||||||||||
More data for this Ligand-Target Pair |