BindingDB logo
myBDB logout

null

SMILES: COC(=O)[C@H](CC(C)C)NC(=O)NC(C(O)=O)c1ccc(O)c(F)c1

InChI Key: InChIKey=YLXIZVWHERFSEY-AMGKYWFPSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304720   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate carboxypeptidase 2


(Homo sapiens (Human))		BDBM50304720
PNG
((S)-2-(3-Fluoro-4-hydroxyphenyl)-2-(3-(1-methoxy-4...)
Show SMILES COC(=O)[C@H](CC(C)C)NC(=O)NC(C(O)=O)c1ccc(O)c(F)c1 |r|
Show InChI InChI=1S/C16H21FN2O6/c1-8(2)6-11(15(23)25-3)18-16(24)19-13(14(21)22)9-4-5-12(20)10(17)7-9/h4-5,7-8,11,13,20H,6H2,1-3H3,(H,21,22)(H2,18,19,24)/t11-,13?/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
 3.00E+3n/an/an/an/an/an/an/an/a



Institutions

Curated by ChEMBL


Assay Description
Inhibition of glutamate carboxypeptidase 2 in human LNCaP cells by fluorescence based NAALADase assay

Bioorg Med Chem Lett 20: 392-7 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.061
BindingDB Entry DOI: 10.7270/Q2SN092X
More data for this
Ligand-Target Pair