BindingDB logo
myBDB logout

null

SMILES: CC(C)(C)c1ccc(CCC(=S)NCc2ccc(NS(C)(=O)=O)cc2C(F)(F)F)cc1

InChI Key: InChIKey=QDXCHOJFXREFOV-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304756   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Rattus norvegicus (rat))		BDBM50304756
PNG
(3-(4-tert-Butylphenyl)-N-[4-(methylsulfonamido)-2-...)
Show SMILES CC(C)(C)c1ccc(CCC(=S)NCc2ccc(NS(C)(=O)=O)cc2C(F)(F)F)cc1
Show InChI InChI=1S/C22H27F3N2O2S2/c1-21(2,3)17-9-5-15(6-10-17)7-12-20(30)26-14-16-8-11-18(27-31(4,28)29)13-19(16)22(23,24)25/h5-6,8-11,13,27H,7,12,14H2,1-4H3,(H,26,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.40E+3n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neurons assessed as inhibition of capsaicin-induced [45]Ca2+ uptake

Bioorg Med Chem 17: 8149-60 (2009)


Article DOI: 10.1016/j.bmc.2009.10.043
BindingDB Entry DOI: 10.7270/Q2NV9JBN
More data for this
Ligand-Target Pair