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SMILES: Clc1nc(N2CCNCC2)c2scc(-c3ccccc3)c2n1

InChI Key: InChIKey=NKNFFXNMVSDGOP-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304824   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50304824
PNG
(2-chloro-7-phenyl-4-(piperazin-1-yl)thieno[3,2-d]p...)
Show SMILES Clc1nc(N2CCNCC2)c2scc(-c3ccccc3)c2n1
Show InChI InChI=1S/C16H15ClN4S/c17-16-19-13-12(11-4-2-1-3-5-11)10-22-14(13)15(20-16)21-8-6-18-7-9-21/h1-5,10,18H,6-9H2
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n/an/a 540n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity against human 5HT2C receptor by FLIPR assay

Bioorg Med Chem Lett 20: 266-71 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.112
BindingDB Entry DOI: 10.7270/Q2154H5M
More data for this
Ligand-Target Pair